Explore Our Portfolio
Get to know some of the many startups to have emerged from ÐÇ¿Õ´«Ã½.
Afference
Afference has made a glove that uses neural simulation to create artificial sensations and touch during digital interactions. Any device can be used to wirelessly connect and make it work. .
Amrit/Picture Health
Picture Health used Innoplexus technology to create the Curia app and bring current, accurate and relevant information to cancer patients. .
Anemed
Anemed aims to create a device that helps people who suffer from sleep apnea; a 3-D printed custom made oral appliance similar to a dental retainer. .
Atelerix
The Atelerix method encapsulates cells in alginate gel, keeping them safe during storage and transport, and then releasing them ready-to-use when they reach their destination. .
BioChip Labs
BioChip labs analyses blood cells using over ten different laboratory test types, diagnosing disease such as sickle cell disease and thalassemia. .
BIOHM
Biohm makes a variety of probiotics to improve gut health. Their "Total Probiotic" won Microbiome Modulation Product of the Year. .
BioInvision
Provider of cryo-imaging services intended to offer cellular and molecular imaging functions. The company's cryo-imaging services help in detection of fluorescently tagged stem or cancer cells using multi-spectral fluorescence imaging tools, enabling clients to examine disease or therapeutic processes using various imaging techniques. .
Calida Therapeutics
Calida Therapeutics’ ambition is to become a leader in the new field of thrombo-inflammatory disorders. Its mission is to develop monoclonal antibodies to treat and prevent thrombo-inflammatory disorders. Its approach is based on more than 20 years of research conducted in Cleveland, U.S., by researchers from the academic and medical ecosystem. .
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The CardioInsightâ„¢ Workstation takes the ECG signals collected by the CardioInsightâ„¢ Mapping Vest and combines them with CT scan data to produce and display simultaneous, bi-atrial and biventricular, 3-D cardiac maps. The workstation and the vest function together as the CardioInsightâ„¢ Noninvasive 3D Mapping. CardioInsight was sold to Medtronic in 2015. .
Collamedix
Collamedix is creating a medical device, known as CollaSling, aims to treat stress urinary incontinence in women—urine leakage coinciding with laughing, coughing, sneezing, lifting and exercise—by using proprietary collagen-based materials to provide structural support to human tissue. .
Convelo Therapeutics
Convelo has developed an innovative and proprietary platform to identify novel drug candidates capable of directly stimulating oligodendrocyte progenitor cells within the CNS to form new myelin. Importantly, Convelo Therapeutics scientists have discovered a central biological pathway that controls myelination in the CNS, including defined drug-targets. These discoveries have allowed Convelo to develop a pipeline of potent drug candidates that are advancing towards clinical testing. .
Edifice Analytics
Edifice Analytics aims to limit energy overconsumption using multiple data point while saving money for businesses. .
Folio Photonics
Folio Photonics is reenergizing storage media innovation with the first-ever enterprise-scale, immutable active archive solution that delivers breakthrough cost, security, and sustainability benefits. They sell long-lived, high capacity, random access storage mediums impervious to the elements — delivered at the lowest cost per TB. .
Global Health Metrics
Global Health Metrics was founded in 2015 by a team of scientists committed to delivering innovative analytics into medical practice. GHM offers Health Risk Assessments to aid people in analyzing their lifestyle choices and assessing what changes can be made for a longer lifespan and healthier life. .
Haima
Haima uses platelet inspired therapy for treating blood-related ailments. Haima’s lead technology, called SynthoPlate, is a novel, fully-synthetic hemostatic agent that mitigates bleeding by acting at the site of injury and amplifying your body’s natural clotting mechanisms. .
Hemex Health
Hemex's Gazelle device tests for hemoglobin disorders within 8 minutes and can be used by anyone. Disorders tested include sickle cell disease (SCD) and beta thalassemia. Early diagnosis could prevent tens of thousands of SCD child deaths each year. .
IlumisAR
IlumisAR's lead product, the HoloAnatomy® Software Suite transforms the way students learn human anatomy. The HoloAnatomy platform uses advanced mixed-reality technology to illuminate the body in 3D. As a result, students learn faster, retain more vital information, and transcend the classroom with unprecedented collaborative potential. .
Intwine Connect
Intwine Connect is a developer of internet technology products designed for monitoring, managing, and optimizing business-critical operations. The company specializes in designing and developing hardware, software, and services including health monitoring, distance learning, and food safety, enabling businesses to improve business processes using Internet of Things (IoT) products and services. .
Molecular Theranostics
Molecular Theranostics is an early stage biotechnology company with a focus on novel imaging technologies. The technologies in the pipelines will address the unmet clinical needs for early detection, risk-stratification, and active surveillance of aggressive cancers and non-invasive assessment of the efficacy of cancer therapies. .
Mosaic ImmunoEngineering
Mosaic ImmunoEngineering Inc is a development-stage biotechnology company focused on bridging immunology and engineering to develop novel immunotherapies to treat and prevent cancer and infectious diseases. The company has a single operating segment for the purposes of assessing performance and making operating decisions. .
NeoIndicate
Neoindicate's lead products recognize tumors using unique biomarkers, and also act as therapeutics targeted for brain tumors, melanoma, ovarian, breast, lung and prostrate cancers. .
NeoProteomics
NeoProteomics is a structural biology contract research organization, and is one of the only companies using the specific protein footprinting technique to aid with drug discovery and medicinal chemistry. .
NervGen Pharma
NervGen Pharma aims to develop treatments that would help the nervous system repair itself following injury or disease.Their website states that NervGen’s lead drug candidate, NVG-291, is being evaluated in a Phase 1b/2a clinical trial. .
Neuros Medical‌‌
Neuros Medical developed the product Altius for the treatment of chronic post-amputation phantom limb and residual limb pain. Altius uses Neuros’ patented Bioelectric On-Demand Nerve Block Technology to target pain at the source, the affected peripheral nerves. .
OpsiClear
OpsiClear is a developer of an optical imaging technology designed to improve clinical imaging outcomes. The company's imaging technology uses advanced 3D imaging and sample processing techniques, enabling clients to get accurate and efficient clinical histopathology imaging results. .
Presidio Medical
Presidion is a developer of neuromodulation platforms designed to establish a class of therapeutic medical devices. The company's platform is created using biotechnology and is developing a bioelectronic medicine for fundamental neuromodulation to establish a new class of therapeutic medical devices, enabling patients to get cures for diseases of neural activities. .
RoadPrintz
RoadPrintz is a manufacturer of robotic road painting equipment intended to specify and apply paint schemes on roads in minutes. The company's equipment increases road safety by making effective visual street markings more affordable and accessible via robotic street painting, enabling traffic engineers and road painting contractors to reduce the risk of accidents and maintain road safety through enhanced markings. .
Rora Biologics
Rora Biologics is a developer of a T-cell platform designed to provide innovative cell therapies including genetically engineered chimeric antigen receptor T cells to treat cancer patients. The company's platform provides recently discovered stem cell-like memory T cells for making chimeric antigen receptor drugs durable, safer, and long-lasting, along with stand-alone therapy to reconstitute the immune system that is affected by human immunodeficiency viruses infection, enabling healthcare professionals to improve treatment for patients. .
SHC Therapeutics
SHC Therapeutics is a developer of an HIV "vaccine" designed to allow HIV patients latency periods of 12-24 months without treatment, after a few weeks of treatment regimen.
Synapse Biomedical Inc.‌‌
The main product of Synapse Biomedical Inc. is the NeuRx DPS®. Their groundbreaking neurostimulation implant technology is approved by the U.S. Food and Drug Administration (FDA) for treating people with spinal cord injuries (SCI) and ALS patients. With no moving parts, noiseless operation, and its small size, the state-of-the-art NeuRx DPS® is engineered to help you breathe naturally and live more comfortably. .
Tevard
Tevard is a developer of tRNA-based gene therapies designed to address and correct underlying genetic mutations in a precise and regulated manner. The company uses mRNA stabilization and codon suppression to cure rare and severe genetic diseases, helping patients in repairing and restore the expression of genes to their normal levels. .
Trailhead Biosystems
Trailhead Biosystems is a developer of a biotechnology drug and cell therapies designed for the advanced production of various therapeutics. The company merges developmental biology and cell therapeutics with hardware and computerized experimental design and analysis to perform process-specific parameter optimization for customers seeking to develop cell therapies, enabling healthcare clients to reduce the number of experiments and time otherwise needed for running one-factor-at-a-time experiments to optimize a large number of variables. .
XaTek
XaTek® Inc., a Cleveland-based privately held company, develops technologies to fulfill urgent and emerging healthcare needs. Its ClotChip® device, a portable point-of-care device, provides quantitative and qualitative diagnostic evaluation of a patient’s entire hemostatic process. This device is the realization of XaTek's mission to provide accurate, non-invasive, point-of-care visibility to a patient’s blood clotting risk profile. .