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Colleen Croniger, PhD
Associate ProfessorDepartment of NutritionSchool of MedicineAssistant DeanBasic Science EducationSchool of MedicineAssistant ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineEmail: colleen.croniger@case.edu
Phone: 216.368.4967
My research involves metabolism, CAAT/enhancer binding protein beta (C/EBP beta), transcription, Phosphoenolpyruvate carboxykinase (PEPCK), knockout animal models, and perinatal metabolism.
Xinghong Dai, PhD
Assistant ProfessorDepartment of Physiology and BiophysicsSchool of MedicineEmail: xxd159@case.edu
Phone: 216.368.5131
We use cryo-electron microscopy (cryoEM) as the major tool for structure-guided antiviral drug discovery and vaccine design. Current focuses are human herpesviruses and hepatitis B virus.
David Schwartz PhotographyDavid Danielpour, PhD
ProfessorCase Comprehensive Cancer CenterAssociate ProfessorDepartment of UrologySchool of MedicineAssociate ProfessorDepartment of PharmacologySchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: dxd49@case.edu
Phone: 216.368.5670
My lab focuses on function and regulation of TGF-ß and BMP in the prostate and prostate cancer, as well as oncogenic function of JAB1, therapeutic control of IGF-I/PI3K/Akt/mTOR and AMPK signaling.
David Danielpour's Biography
Piet de Boer, PhD
ProfessorDepartment of Molecular Biology and MicrobiologyEmail: pad5@case.edu
Phone: 216.368.1697
Our lab studies bacterial molecular genetics, biochemistry and cell biology, and the formation of the division septum and related cell cycle events.
Michael J. Decker, PhD, RN, RRT, D.ABSM
Associate ProfessorDepartment of Physiology and BiophysicsSchool of MedicineAssociate ProfessorDepartment of NeurosciencesSchool of MedicineAssociate ProfessorFrances Payne Bolton School of NursingEmail: mjd6@case.edu
Phone: 216.368.2912
I study systems neurophysiology related to aerospace environments, and high speed flight, hypergravity, weightlessness, hypoxia, and hyperoxia.
Evan Deneris, PhD
Professor and Interim ChairDepartment of NeurosciencesSchool of MedicineEmail: esd@case.edu
Phone: 216.368.8725
I focus on gene regulatory networks controlling brain serotonin neuron transcriptomes, chromatin dynamics, axon architectures and serotonin-modulated behaviors.
Andrew Dhawan, MD, PhD
Associate StaffCleveland ClinicMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: dhawana@ccf.org
My research program is focused on using translational data science, computational biology, and mathematical biology to more accurately diagnose, treat, and prognosticate in neurological disorders.
J. Alan Diehl, PhD
ChairDepartment of BiochemistrySchool of MedicineProfessorDepartment of BiochemistrySchool of MedicineDeputy Director for ÐÇ¿Õ´«Ã½Case Comprehensive Cancer CenterMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: jad283@case.edu
Phone: 216.368.0268
I research cell cycle regulation, acquired resistance to CDK4/6 inhibitors, ubiquitin-dependent protein degradation, unfolded Protein Response and Tumor Progression, Non-coding RNA, and the circadian clock.
Curtis J. Donskey, MD
Professor of MedicineDivision of Infectious Diseases & HIV MedicineSchool of MedicineEmail: curtis.donskey@case.edu
Phone: 216.791.3800
I focus on mechanisms by which intestinal microflora inhibit colonization by pathogens, in addition to transmission of C diff and other nosocomial pathogens.
Afshin Dowlati, MD
ProfessorDepartment of MedicineDivision of Hematology and OncologySchool of MedicineAssociate Director for Clinical ResearchCase Comprehensive Cancer CenterMemberDevelopmental Therapeutics ProgramCase Comprehensive Cancer CenterEmail: axd44@case.edu
Phone: 216.844.1228
A significant effort of our research lab is to identify novel therapeutics for small cell lung cancer. There has been little progress in the clinical management of this disease over the last three decades due mainly to our limited knowledge about the underlying mechanisms driving this malignancy. Our research is focused on the basic and translational aspects of target validation and drug development, and we are also uniquely positioned to perform preclinical studies of novel drugs in cancer models with the eventual goal of taking them into the clinic.