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Scott Williams, PhD
ProfessorDepartment of Population and Quantitative Health SciencesSchool of MedicineProfessorDepartment of Genetics and Genome SciencesSchool of MedicineFacultyCleveland Institute for Computational BiologyEmail: smw154@case.edu
Phone: 216.368.5659
I investigate the distribution of genetic variation and the role that this variation plays in phenotypic differences among populations, including the role of host pathogen co-evolution in infectious disease risk.
Mark Willis, PhD
Professor and ChairDepartment of BiologyCollege of Arts and SciencesEmail: mark.willis@case.edu
Phone: 216.368.3557
I research the neural basis of adaptive behavior, odor-guided navigation and flight in insects.
JungA ‘Alexa’ Woo, PhD
Associate ProfessorDepartment of PathologySchool of MedicineEmail: Jaw330@case.edu
Phone: 216.368.0052
Our lab focuses on understanding how beta-arrestins, proteins known to regulate various GPCRs signaling (~40% of FDA-approved drugs target GPCRs), contribute to neurodegeneration in Alzheimer’s disease (AD) and related dementias (ADRD).
Chen-Han Wilfred Wu, MD, PhD
Assistant ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineAssistant ProfessorDepartment of UrologySchool of MedicineDirectorUrogenetics ProgramMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterSchool of MedicineEmail: wilfred.wu@case.edu
Phone: 216.368.0837
Our lab is at the forefront of genomics in urological conditions, leveraging large datasets from both phenotypic information gleaned from electronic medical records (EMR) and genomic data from comprehensive sequencing techniques. We offer the unique experience of working in both dry and wet lab environments, with data access to resources like the UK Biobank, All-of-Us, TriNetX, University Hospitals EMR, and our in-house experiments. Our current active projects span areas such as kidney stones, male infertility, and transgender studies, providing a rich and diverse research environment to advance your academic career.
Tsan Sam Xiao, PhD
ProfessorDepartment of PathologySchool of MedicineMemberDevelopmental Therapeutics ProgramCase Comprehensive Cancer CenterMemberCenter for AIDS ResearchSchool of MedicineMemberCleveland Center for Membrane and Structural BiologyEmail: tsan.xiao@case.edu
Phone: 216.368.3330
My research focuses on structural and function of gasdermin family members in pyroptosis and inflammatory cytokine secretion, Molecular mechanisms of inflammasome activation during viral infection such as SARS-CoV-2, and Activation and substrate recognition by inflammatory caspases in health and disease.
Liangqi Xie, PhD
Assistant StaffCancer BiologyLerner Research Institute, Cleveland ClinicMemberCancer Imaging ProgramCase Comprehensive Cancer CenterEmail: xiel2@ccf.org
We are interested in using high-resolution microscopy and high-throughput genomics to understand genome regulation in human development and diseases.
Wen-Cheng Xiong, MD, PhD
Riuko and Archie G. Co ProfessorDepartment of NeurosciencesSchool of MedicineEmail: wxx119@case.edu
Phone: 216.368.4865
I study molecular mechanisms underlying neural development, neuro-degeneration, and bone homeostasis.
Rong Xu, PhD
Professor of Biomedical Informatics, DirectorCenter for AI in Drug DiscoverySchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterSchool of MedicineEmail: rxx@case.edu
Phone: 216.368.0023
We are interested in developing innovative artificial intelligence, natural language processing, data mining, machine learning, pattern recognition, graph theory, systems biology, knowledge representation and engineering, ontology and other computational algorithms to automatically understand genetic causes of diseases, identify candidate drugs/compounds to treat diseases, elucidate how environmental factors contribute to diseases, and conduct health outcomes research.
Sichun Yang, PhD
Associate ProfessorDepartment of NutritionSchool of MedicineAssociate ProfessorCenter for Proteomics and BioinformaticsSchool of MedicineAssociate ProfessorDepartment of PharmacologySchool of MedicineAssociate ProfessorDepartment of Physiology and BiophysicsSchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: sichun.yang@case.edu
Phone: 216.368.5793
My research is in estrogen receptor biophysics, cancer biology, and drug discovery.
Vivien C. Yee, PhD
Associate ProfessorDepartment of BiochemistrySchool of MedicineDirector of Undergraduate Programs and Vice Chair for EducationDepartment of BiochemistrySchool of MedicineAssociate ProfessorDepartment of PharmacologySchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: vivien.yee@case.edu
Phone: 216.368.1184
I research the determination of protein molecular structure using X-ray diffraction and correlation with function.