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My focus is in molecular mechanisms of the antitumor and antiviral activities of interferons. 

My research includes prion diseases, protein transport, chaperones, proteasomes, and nuclear import. 

Neena Singh's Biography 

I research HIV-host cell interaction and accessory proteins.

Jacek Skowronski's Biography 

I research cell physiology, neural circuits and synaptic plasticity, systems neuroscience, neuroendocrinology, autonomic regulation, cardiovascular neuromodulation, and electrophysiology. 

I primarily research cholesterol metabolism by macrophages, the genetics of atherosclerosis susceptibility in mouse models, and genetics and drug discovery in mouse models of Alzheimer disease.

We communicate with our resident microbiota through the language of metabolites. Host-derived metabolites shape the balance between commensals and pathogens, and in turn, microbiota-derived metabolites tune host immune responses. This dialogue ultimately determines our susceptibility to disease. We use bacterial genetics, genomics, animal models, and immune profiling to decipher microbiota-host metabolic communication in the oral cavity, site of one of the most prevalent inflammatory diseases worldwide (periodontitis).

My primary research is in redox-based cellular regulation and signal transduction, and in particular the role of protein S-nitrosylation. 

Dr. Catherine M. Stein’s primary research focus is on genetic and environmental susceptibility to tuberculosis (TB), specifically the genomics of resistance and how genetic variation in both humans and the tuberculosis pathogen influence TB severity. Dr. Stein also works on speech-sound disorder, building upon more than two decades of ÐÇ¿Õ´«Ã½ study.

Catherine M. Stein's Biography

Our lab studies molecular and in vivo mechanisms of cardiac regulation. We focus on the role of contractile proteins in modulation of mechanical and hemodynamic function in genetic and aquired heart failure. We use biophysical techniques, in vivo cardiovascular phenotyping, and gene replacement approaches to develop novel therapies that improve contractile function in heart failure.

Our lab focuses on the physiology of mechanosensory cells of the inner ear; receptors for senses of hearing and balance; in mouse and zebrafish models; electrophysiology, optical and electron microscopy imaging.