From molecules to the bedside

Forefront | Summer 2021

How donor support is shaping the field of nursing


By Carey Skinner Moss

Wearing face masks, Associate Dean for Research Ron Hickman (left) and PhD alumna Julia O'Brien pose for a photo in the HEC.
Professor Ronald Hickman Jr. with PhD alumna and mentee Julia O'Brien.

The U.S. Bureau of Labor Statistics projects the United States will need another 1.1 million nurses by 2022. But the shortage goes beyond the bedside. Nurse scientists are needed to develop and test interventions to improve patient health.

鈥淒onor support is critical. Research is critical,鈥 said Joachim Voss, PhD, ACRN, FAAN. Voss is the director of the PhD program at 星空传媒鈥檚 Frances Payne Bolton School of Nursing and the Independence Foundation Professor in Nursing Education. 

Of particular interest to Voss is the new Derry Ann Moritz Scholarship鈥攁 unique opportunity for nursing school PhD candidates whose dissertations focus on palliative or end of life care. Moritz (NUR 鈥58) established this scholarship in honor of her friend Barbara Daly, PhD, RN (NUR 鈥72), a 星空传媒 Distinguished University Professor Emerita and the Gertrude Perkins Oliva Professor Emerita of Oncology Nursing whose life鈥檚 work has focused on addressing the unique challenges that come with treating critically and chronically ill patients.

鈥淧alliative and end of life care don鈥檛 typically receive a lot of attention from funders,鈥 Voss shared, 鈥渁nd when they do, support is often focused on a specific disease, such as cancer.鈥

While disease-specific research is important, the wide scope of the Moritz scholarship will allow for a greater variety of diseases and circumstances to be studied, which benefits patients and scientists alike.

PhD students can leave the school knowing they have contributed to meaningful research鈥攁nd that they will have their choice of career opportunities.

Opening doors

鈥淲e [as faculty] are not doing our jobs unless our graduates get jobs,鈥 Voss emphasized, 鈥渂ut a PhD is a key that opens many doors.鈥 Nurses with PhDs can apply their expertise as policy makers, design cutting-edge pharmaceutical supplies, become faculty members at nursing schools, or continue vital research.

For Julia O鈥橞rien, PhD (CWR 鈥14; GRS 鈥21, nursing and advanced quantitative methodologies), the doors are open wide post-graduation.

O鈥橞rien received the Joyce M. Stielau Award in spring 2021 for her research on sickle cell disease and social determinants of health. The late Joyce M. Stielau was a nurse anesthesiologist, devoted hospital volunteer and philanthropist. The research award she established enabled O鈥橞rien to collect data from a larger sample size during the pandemic, in addition to offering a raffle for participants.

鈥淲ithout awards like this, it would be difficult to complete these projects,鈥 said O鈥橞rien. 鈥淲hen you鈥檙e studying a less common disease, one that affects approximately 100,000 [Americans], finding resources can be difficult, especially as a graduate student. This support allows someone like me to move forward in my career and hopefully be able to give back one day to 星空传媒, to the nursing profession and to the broader patient community.鈥

O鈥橞rien began her undergraduate studies at the nursing school with the intention of practicing in a clinical setting, but changed course because of the mentorship she received. 鈥淭here were mentors at 星空传媒 who were willing to take me under their wing鈥攁nd not just to give me a job doing a little number crunching,鈥 she reflected. During a research retrospective, for example, faculty members took O鈥橞rien to an outpatient clinic at University Hospitals to meet patients with sickle cell disease.

鈥淚t helped me understand where there were health disparities among this population, and that is part of what made me realize there was a lot of important work to be done,鈥 O鈥橞rien remarked on the experience. 鈥淚 certainly hope to be that person for students moving forward.鈥

O鈥橞rien is now pursuing a postdoctoral fellowship at the University of Pittsburgh, where she will build on the research supported by the Stielau award to study technology-related interventions for adults and adolescents with sickle cell disease. She hopes the impact of the resources will be applicable for many patients with chronic pain.

Solving today鈥檚 most pressing issues

The Stielau award and the Moritz scholarship are two of three new donor-funded opportunities available to PhD students.

The third鈥攖he Donna Algase Dissertation Award鈥攇rants funding for early-stage research in the field of eldercare. And that research is of particular importance now with a rapidly aging population.

As of 2019, 71 million Americans were over the age of 65鈥攖he highest number in the nation鈥檚 history. And with better and more accessible health care, that number is expected to continue rising and, along with it, the health care needs of this population.

鈥淭hese young people, through the Algase, Moritz and Stielau gifts, can really make a meaningful impact on palliative care, on eldercare and on nursing science in general,鈥 said Ronald Hickman Jr., PhD, RN (CWR 鈥00; NUR 鈥02, 鈥06, 鈥13; GRS 鈥08, nursing), the school鈥檚 associate dean of research and the Ruth M. Anderson Professor. 鈥淢ost times we think about nurses caring for people at the bedside, but there鈥檚 also a group of nurse scientists generating new knowledge that we all benefit from. Donna Algase is interested in understanding the molecular basis as well. So these awards are truly funding work from molecules to the bedside, which I think is fascinating.鈥

A 40-year victory

Donna L. (Muszynski) Algase, PhD (GRS '88, nursing) has waited a long time for nursing science to be truly valued for its contributions to the field of medicine. 鈥淣ursing has always been kind of an underdog in a lot of ways,鈥 she commented. Algase鈥檚 work is in the area of dementia and behavioral problems, specifically the troubling issue of wandering.

鈥淭here is some research into wayfinding and how the brain operates to encode that information, but very little research has been done on the molecular basis of [wandering],鈥 Algase said. She first started this research about 40 years ago and, even though she was awarded a grant to study the phenomenon, her theories were mocked by a pharmacologist she worked with. 鈥淚t was insulting, not to me personally, but to nursing, period.鈥

Then last year she was approached by a pharmaceutical company to be a consultant. They secured the rights to sell a cardiac medication developed in Japan that, in some anecdotal reports, showed a decrease in wandering behavior for patients with dementia.

鈥淭his company looked me up after almost 10 years of retirement, and my work was still relevant. So it came full circle, from a pharmacologist dismissing my research to a pharmaceutical company contacting me 40 years later to help them evaluate this potential treatment. That was incredible to me,鈥 she chuckled.

Giving back to shape the future

Algase, like O鈥橞rien, was inspired by the mentorship and leadership at 星空传媒. Even after joining the faculty at the University of Michigan, Algase maintained a close connection to her alma mater and received the nursing school鈥檚 Outstanding Alumni Award in 2004. 鈥淚t felt like I never really left, in a fashion鈥攖hat there was a part of me still there,鈥 she said. 鈥淪o when I had the good fortune to make this kind of donation, 星空传媒 was certainly high on my list.鈥

Seventy percent of the school鈥檚 graduate-level students receive scholarship or fellowship assistance, with donor support proving vital in reducing barriers to access for students鈥攅specially at a time when the field is experiencing a declining trend in PhD training and nursing science.

鈥淚t鈥檚 a challenging time in nursing education, particularly at the doctoral level because of the shortage,鈥 Algase continued. 鈥淭he more support we can make available to attract students of all backgrounds to [the PhD] route, the better off we are. 鈥 If they have a scientific mind, if they have an interest in caring, we need them.鈥

To learn more about the donors mentioned in this article or to apply for one of these awards, please visit case.edu/nursing or email fpbdevelopment@case.edu.

From molecules to the bedside