Research Information
Research Interests
Dr. Dobbs’ research interests include innate immunity to malaria and childhood infections of global health significance. She is currently principal investigator of a career development award studying monocyte-mediated immune responses to pediatric malaria. Current projects include determining the mechanisms underlying changes in monocyte function during malaria and understanding the role that epigenetic reprogramming plays in innate immune responses to malaria infection.
Publications
Dobbs K and Dent E. Plasmodium malaria and antimalarial antibodies in the first year of life.
Parasitology 2016;143(2):129.
(https://www.ncbi.nlm.nih.gov/pubmed/26743626)
Dobbs K, Embury P, Odada-Sumba P, Vulule J, Rosa B, Mitreva M, Kazura J, Dent A. Monocyte dysregulation and systemic inflammation during pediatric falciparum malaria. 2017. JCI Insight, Sep 21;2(18).
(https://www.ncbi.nlm.nih.gov/pubmed/28931756)
Schrum JE, Crabtree JN, Dobbs KR, Kiritsy MC, Reed GW, Gazzinelli RT, Netea MG, Kazura JW, Dent AE, Fitzgerald KA, Golenbock DT. Plasmodium falciparum induces trained innate immunity. J Immunol, January 12, 2018, ji1701010.
(https://www.ncbi.nlm.nih.gov/pubmed/29330325)