Speaker: Dominique M. Durand, PhD
EL Lindseth Professor of Biomedical Engineering and Distinguished University Professor
Director, Neural Engineering Center
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Abstract: The presentation will discuss a novel approach for suppressing difficult-to-treat cortical focal seizures. The approach utilizes fiber tract low frequency stimulation, which has been shown to be effective in both animal and human studies for mesial temporal lobe seizures. This stimulation targets the axons of the corpus callosum innervating the focal zone at low frequencies (5 to 10Hz) and has been shown to significantly reduce both seizure and spike frequency in rodents. The stimulation is selective to the focal region and works by activating both GABAB and AHP in targeted neurons, providing a promising new option for individuals suffering from cortical focal seizures.
About the Speaker: Dr. Dominique M. Durand is a Distinguished University Professor of Biomedical Engineering and the Director of the Neural Engineering Center at ÐÇ¿Õ´«Ã½ in Cleveland, Ohio. He received degrees from Ecole Nationale Superieure of Toulouse, Case Reserve University, and the University of Toronto. He is an IEEE Fellow, AAAS Fellow, and AIMBE Fellow, serves on many editorial boards and is the founding editor of the Journal of Neural Engineering. His research focuses on controlling seizures in epilepsy patients, developing devices to communicate with the nervous system, and understanding brain waves.
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