In person in Sears 439
Speaker: Costa Tsiptsis
Advisor: Prof. A. Shoffstall
Abstract: Hypertension is a leading cause of death globally, and affects nearly half of adults in the United States. Baroreceptor activation therapy (BAT) offers a promising approach for managing hypertension by surgically placing a small electrode on the carotid sinus to stimulate afferent baroreceptor fibers and modulate the baroreflex. Despite its potential, more than half of BAT patients experience adverse effects that may limit its therapeutic efficacy. Research suggests these side effects are not related to stimulation parameters but may stem from anatomical variations between individuals. This presentation will examine the anatomy relevant to BAT, highlight common anatomical variations reported in the literature, and investigate the likely origins of off-target effects. Additionally, the use of microcomputed tomography and immunohistochemistry will be discussed for their roles in studying gross and microscopic anatomy.
- Home
- node
- 1016
Identifying potential sources of off-target effects from baroreceptor activation therapy using microcomputed tomography and immunohistochemistry
Event Date:
October 25th 9:00 AM - 10:00 AM