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Kenneth J. Gustafson, PhD

Associate Professor
Department of Biomedical Engineering
Case School of Engineering
School of Medicine

Teaching Information

Teaching Interests

Bioelectric Engineering, Biomedical Devices & Instrumentation, Physiology, Modeling, Professional Development

Research Information

Research Interests

Professor Gustafson's research is in the areas of neural engineering and neural prostheses. His research interests focus on understanding the systems-level neurophysiology and neural control of pelvic functions, and using this information to design and develop neural prostheses that interface with native spinal neural circuitry and restore physiologic function. Lower urinary tract dysfunction can have a devastating clinical impact. Therefore his efforts include developmental and pre-clinical studies to translate research advances into clinical implementation at the earliest opportunity.

Current projects in both animal models and individuals with neural dysfunction include peripheral activation of spinal circuits to activate and inhibit bladder function, development of an implanted neural prosthesis able to selectively record and stimulate neural pathways and restore bladder function, exploring neural anatomy fundamentals to improve peripheral nerve electrode design, neural recording of organ activity as a control source for closed-loop neural prostheses, commercial activities to translate research discoveries into clinical practice, and combining neuromuscular stimulation and myoplasty to harness skeletal muscle power for cardiac assist and rehabilitation applications.

Publications

  • Nicolai, E., Settell, M., Knudsen, B., McConico, A., Gosink, B., Trevathan, J., Baumgart, I., Ross, E., Pelot, N., Grill, W., Gustafson, K. J., Shoffstall, A. J., Williams, J. J., & Ludwig, K. J. (2020). Sources of off-target effects of vagus nerve stimulation using the helical clinical lead in domestic pigs. Journal of Neural Engineering, 17 (4).
  • Settell, M., Pelot, N., Knudsen, B., Dingle, A., McConico, A., Nicolai, E., Trevathan, J., Ezzell, J., Cross, M., Gustafson, K. J., Shoffstall, A. J., Williams, J. J., Zeng, X. J., Poore, S. J., Populin, L. J., Suminski, A. J., Grill, W. J., & Ludwig, K. J. (2020). Functional vagotopy in the cervical vagus nerve of the domestic pig: implications for the study of vagus nerve stimulation.. Journal of neural engineering, 17 (2), 026022.
  • Settell, M., Pelot, N., Knudsen, B., Dingle, A., McConico, A., Nicolai, E., Trevathan, J., Ezzell, J., Cross, M., Gustafson, K. J., Shoffstall, A. J., Williams, J. J., Zeng, X. J., Poore, S. J., Populin, L. J., Suminski, A. J., Grill, W. J., & Ludwig, K. J. (2020). Functional vagotopy in the cervical vagus nerve of the domestic pig: Implications for the study of vagus nerve stimulation.. Journal of neural engineering.
  • Bourbeau, D., Aamoth, K., Brose, S., & Gustafson, K. J. (2019). Electrical Colon Stimulation Reflexively Increases Colonic Activity. Neuromodulation: Techhnology at the Neural Interface.
  • Yeh, S., Lin, B., Chen, S., Chen, C., Gustafson, K. J., Bourbeau, D. J., Rajneesh, C. J., & Peng, C. J. (2019). Effects of Genital Nerve Stimulation Amplitude on Bladder Capacity in Spinal Cord Injured Subjects. Evidence-Based Complementary and Alternative Medicine, 2019 , 1-9.
  • Bourbeau, D., Gustafson, K. J., & Brose, S. J. (2019). At-home genital nerve stimulation for individuals with SCI and neurogenic detrusor overactivity: A pilot feasibility study. Journal of Spinal Cord Medicine, 42 (3), 360-370.
  • Stampas, A., Gustafson, K. J., Korupolu, R. J., Smith, C. J., Zhu, L. J., & Li, S. J. (2019). Bladder Neuromodulation in Acute Spinal Cord Injury via Transcutaneous Tibial Nerve Stimulation: Cystometrogram and Autonomic Nervous System Evidence From a Randomized Control Pilot Trial. Frontiers in Neuroscience, 13
  • Anderson, K., Ajiboye, B. B., Denison, T. B., French, J. B., Gustafson, K. J., Kilgore, K. J., Kleitman, N. J., Kusiak, A. J., Litt, B. J., Moynahan, M. J., Perreault, E. J., Weber, D. J., Williams, J. J., & Tyler, D. J. (2018). Proceedings of the second biennial Cleveland Neural Engineering Workshop 2013. Bioelectronic Medicine, 4 (1).
  • Stampas, A., Korupolu, R., Zhu, L., Smith, C., & Gustafson, K. J. (2018). Safety, Feasibility, and Efficacy of Transcutaneous Tibial Nerve Stimulation in Acute Spinal Cord Injury Neurogenic Bladder: A Randomized Control Pilot Trial: BLADDER NEUROMODULATION OF ACUTE SCI WITH TTNS. Neuromodulation: Techhnology at the Neural Interface.
  • Bourbeau, D., Creasey, G., Sidik, S., Brose, S., & Gustafson, K. J. (2018). Genital nerve stimulation increases bladder capacity after SCI: A meta-analysis. Journal of Spinal Cord Medicine, 41 (4), 426-434.
  • Brose, S., Bourbeau, D., & Gustafson, K. J. (2018). Genital nerve stimulation is tolerable and effective for bladder inhibition in sensate individuals with incomplete SCI. Journal of Spinal Cord Medicine, 41 (2), 174-181.
  • Bourbeau, D., Gustafson, K. J., & Brose, S. J. (2018). At-home genital nerve stimulation for individuals with SCI and neurogenic detrusor overactivity: A pilot feasibility study. Journal of Spinal Cord Medicine.
  • Majerus, S., Fletter, P., Ferry, E., Zhu, C., Gustafson, K. J., & Damaser, M. J. (2017). Suburothelial Bladder Contraction Detection with Implanted Pressure Sensor. PLoS ONE, 12 (1).
  • Bourbeau, D., Creasey, G., Sidik, S., Brose, S., & Gustafson, K. J. (2017). Genital nerve stimulation increases bladder capacity after SCI: A meta-analysis. Journal of Spinal Cord Medicine.
  • Brose, S., Bourbeau, D., & Gustafson, K. J. (2017). Genital nerve stimulation is tolerable and effective for bladder inhibition in sensate individuals with incomplete SCI. Journal of Spinal Cord Medicine.
  • McCoin, J., Bhadra, N., Brose, S., & Gustafson, K. J. (2015). Does Patterned Afferent Stimulation of Sacral Dermatomes Suppress Urethral Sphincter Reflexes in Individuals With Spinal Cord Injury?. , 34 (3), 219-223.
  • Wark, H., Black, SR, H., Mathews, K., Cartwright, P., Gustafson, K. J., & Normann, R. J. (2015). Restoration From Acute Urinary Dysfunction Using Utah Electrode Arrays Implanted Into the Feline Pudendal Nerve. , 18 (4), 317-323.
  • Hopfer, U., Triolo, R., Elias, A., Kilgore, K., DiMarco, A., Bogie, K., Vette, A., Audu, M. L., Kobetic, R. L., Chang, S. L., Chance, M. L., Dukelow, S. L., Bourbeau, D. L., Brose, S. L., Gustafson, K. J., Kiss, Z. J., & Mushahwar, V. J. (2014). Functional electrical stimulation and spinal cord injury.. Physical medicine and rehabilitation clinics of North America, 25 (3), 631-54, ix.
  • Grinberg, Y., Schiefer, M., Tyler, D. J., & Gustafson, K. J. (2008). Fascicular perineurium thickness, size, and position affect model predictions of neural excitation. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 16 (6), 572--581.
  • Bhadra, N., Kilgore, K., & Gustafson, K. J. (2006). High frequency electrical conduction block of the pudendal nerve.. Journal of neural engineering, 3 (2), 180-7.

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Education

PhD
Arizona State University
1997

Additional Information