Understands and solves problems in biology and medicine using transport principles.
Interests: Biotransport applications to Cell and Tissue Engineering, Microvascular tissue engineering
Research Information
Research Interests
Microvascular Tissue Engineering: Tissue engineering has the potential to revolutionize healthcare. A significant challenge in tissue engineering is to overcome substrate mass transfer limitations, which if ignored can result in a product that will not function adequately. The main goal of this research is to design and build microvascular flow analogs that can be used to overcome nutrient limitations in tissue-engineered products. Cell Transport: Cell transport is important in several physiological and pathological processes such as inflammation, embryogenesis, cancer metastasis and wound healing. Several mechanisms of cell transport have been identified: passive transport through random diffusion and active transport via convection and mechanisms such as chemotaxis, chemokinesis, and haptotaxis. The main goal of this research is to understand various mechanisms of cell transport and to modulate the growth of cell monolayers.
Professional Memberships
Publications
- Fattahi, P.; Rahimian, A.; Kihak, G.; Gonzalez-Suarez, A.; Slama, M.; Wolf, J.; Baskaran, H.; Stybayeva, Peterson, Q.; Duffy, C.; and Revzin, A.: Encapsulation and differentiation of human pluripotent stem cells in core-shell hydrogel microcapsules. Scientific Reports, 2021, (Accepted)
- Gong, X.; Yang, P.; Rohm, K.; Zhong, Y.; Zhao, B.; Manas-Zloczower, I.; Baskaran, H.; and Feke. D.L.: Porous hollow fibers with controllable structures templated from high internal phase emulsions. Journal of Applied Polymer Science, 2021, (Accepted)
- Zhong, Y.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Tissue Eng Part A. 2021 Jan 26. doi: 10.1089/ten.TEA.2020.0144. Online ahead of print. PMID: 33499734
- Chariou, P.L.; Dogan, A.B.; Welsh, A.G.; Saidel, G.M.; Baskaran, H.; and Steinmetz, N.F.: . Nat Nanotechnol. 2019 14(7):712-718. doi: 10.1038/s41565-019-0453-7. PMID: 31110265, PMCID: PMC6988359
- Zhong, Y.; Motavalli, M.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: . Annals of Biomedical Engineering, 46(11):1896-1910, 2018, PMID: 29948374, PMCID: PMC6204100
- Wang, K-C.; Egelhoff, T.T.; Caplan, A.I.; Welter, J.F.; Baskaran, H.: , Tissue Engineering Part A, 2018, PMID: 29397789, PMCID: PMC6080111
- Chou, C.L.; Rivera, A.L.; Williams, V.; Welter, J.F.; Mansour, J.M.; Drazba, J.A.; Sakai, T.; and Baskaran, H.: . Acta Biomater. 2017 15(60):210-219 PMID: 28709984 PMCID: PMC5581212
- Chung, C.Y.; Heebner, J.; Baskaran, H.; Welter, J.F.; and Mansour, J.M.: . Ann Biomed Eng. 2015 43(12):2991-3003.
- Thomas, D.G.; Yenepalli, A.; Denais, C.M.; Rape, A.; Beach, J.R.; Wang, Y.L.; Schiemann, W.P.; Baskaran, H.; Lammerding, J.; and Egelhoff, T.T.: . Journal of Cell Biology. 2015, 210(4):583-594. doi: 10.1083/jcb.201502039.
- Rivera, A.L. and Baskaran, H.: The effect of biomolecular gradients on mesenchymal stem cell chondrogenesis under shear stress. Micromachines 2015, 6(3):330-346. doi:10.3390/mi6030330.
- Prologo, J.D.; Duesler, L.; Berilla,J.A.; Baskaran, H.; Schluchter, M.D.; and Welter, J.F.: . Journal of Vascular and Interventional Radiology 2014 (Submitted)