Research Information
Research Interests
Prior to my training at The Ohio State University and Bruker BioSpin Corp., I had 10 years of experience in small molecule synthesis, new reagents development, and large-scale production of drug-like compounds. Since turning my focus to molecular imaging and cardiovascular disease about eight years ago, I have developed contrast agents for magnetic resonance imaging (MRI) of atherosclerosis and discovered new mechanisms by which inflammation regulates atherogenesis, adiposity, and metabolic syndrome in various experimental disease models and environmental settings. Today, I have a substantial track record in drug and imaging probe delivery, MRI system development, and imaging of metabolic diseases.
Research Projects
Our research team develops nanotechnology tools to better understand cardiometabolic diseases such as atherosclerosis, type 2 diabetes and obesity. We engineer, make and test new imaging probes, drug delivery vehicles and sensors that help to diagnose and treat these conditions. In addition to imaging and drug delivery projects, our laboratory investigates lipoproteins and their function and metabolic biology of immune cells. We also have long-standing interest in toxicology of synthetic and environmental nano-/microparticles and their effects on cardiometabolic health. Recently, we started to look into cardiovascular biology of incretin peptides, such as glucagon-like peptide-1 to see how these molecules maybe involved in immune cells behavior and anti-atherosclerotic effects.
Publications
- Yao, Zhili, Jessica M. Mates, Alana M. Cheplowitz, Lindsay P. Hammer, Andrei Maiseyeu, Gary S. Phillips, Mark D. Wewers, et al. 2016. . Journal of Immunology 197 (6): 2390–92
- Maiseyeu, Andrei. 2016. Advanced Drug Delivery Reviews 99 (Pt A):
- Bagalkot, Vaishali, Jeffrey A. Deiuliis, Sanjay Rajagopalan, and Andrei Maiseyeu. 2016. ‘. Advanced Drug Delivery Reviews 99 (Pt A): 2–11.
- Ganesan, Latha P., Jessica M. Mates, Alana M. Cheplowitz, Christina L. Avila, Jason M. Zimmerer, Zhili Yao, Andrei Maiseyeu, Murugesan V. S. Rajaram, John M. Robinson, and Clark L. Anderson. 2016. . Scientific Reports 6: 20646.
- Zhong, Jixin, Andrei Maiseyeu, Stephen N. Davis, and Sanjay Rajagopalan. 2015. . Circulation Research 116 (8): 1491–1504.
- Bagalkot, Vaishali, Marcus A. Badgeley, Thomas Kampfrath, Jeffrey A. Deiuliis, Sanjay Rajagopalan, and Andrei Maiseyeu. 2015. . Journal of Controlled Release: Official Journal of the Controlled Release Society 217: 243–55.
- Rao, Xiaoquan, Jixin Zhong, Andrei Maiseyeu, Bhavani Gopalakrishnan, Frederick A. Villamena, Lung-Chi Chen, Jack R. Harkema, Qinghua Sun, and Sanjay Rajagopalan. 2014. . Circulation Research 115 (9): 770–80.
- Maiseyeu, Andrei, and Vaishali Bagalkot. 2014. . Nanoscale Research Letters 9 (1): 176.
- Maiseyeu, Andrei, Hui-Yu Yang, Gajalakshmi Ramanathan, Fen Yin, Robert L. Bard, Masako Morishita, J. Timothy Dvonch, et al. 2014. . Inhalation Toxicology 26 (1): 23–29.
- Giri, Shivraman, Hui Xue, Andrei Maiseyeu, Randall Kroeker, Sanjay Rajagopalan, Richard D. White, Sven Zuehlsdorff, Subha V. Raman, and Orlando P. Simonetti. 2014. . Magn. Reson. Med. 71 (1): 133–44.
- Sharkey-Toppen, Travis P., Georgeta Mihai, Andrei Maiseyeu, Tam Tran, Bradley D. Clymer, Orlando P. Simonetti, and Subha V. Raman. 2013/1. . Magnetic Resonance Imaging 31 (1): 44–52.
- Yang, Fangping, Xulang Zhang, Andrei Maiseyeu, Georgeta Mihai, Rumana Yasmeen, David DiSilvestro, Santosh K. Maurya, et al. 2012. . Biomaterials 33 (22): 5638–49.
- Maiseyeu, Andrei, Marcus A. Badgeley, Thomas Kampfrath, Georgeta Mihai, Jeffrey A. Deiuliis, Cuiqing Liu, Qinghua Sun, et al. 2012. . Arteriosclerosis, Thrombosis, and Vascular Biology 32 (4): 962–70.
Education
Additional Information
- 2013-2016: Assistant Professor of Medicine (Tenure Track), Division of Cardiovascular Medicine, The University of Maryland, Baltimore
- 2012-2013: Research Assistant-Professor, Division of Cardiovascular Medicine, The Ohio State University