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Case-Coulter Translational Research Partnership (CCTRP) RFA
Pre-proposal Due Date: February 28, 2023 

The following information is shared on behalf of the Case-Coulter Translational Research Partnership (CCTRP).

This is the third year of the fifth phase of the Case-Coulter Translational Research Partnership (CCTRP) to support collaborative translational research projects that address unmet or poorly met clinical needs. The CCTRP seeks to reduce the market risk of promising new clinical products arising from the research programs of BME and affiliated Case faculty. Successful projects will thus often focus on the development of prototype products, building relationships with companies, performing clinical feasibility studies, obtaining regulatory approval, and other activities that companies or business experts indicate are the essential last steps before a license can be negotiated or a startup launched. An overarching goal of the program is to foster research and development work likely leading to commercially relevant translational technologies within a three- to five-year horizon. Because the goals of all Coulter projects are to reduce market risk, all proposals are expected to reflect genuine business input, and all projects must include a “business advisor” as an important member of the decision making team.

The funding provided by the CCTRP should be considered as a “cooperative agreement” rather than a “grant”. That is, the CCTRP staff, Technology Transfer Office (TTO) staff, and the Oversight Committee (OC) are partners in the project rather than a funding agency. Faculty should (and will be expected to) take advantage of the unique resources provided by the program and to include program staff in all major decisions. Project PI’s are expected to provide at least monthly updates on progress towards milestones, and timely quarterly reporting from the BME PI of each project will be a milestone of ALL projects and will factor into decisions about continued funding.

The CCTRP awards funding at 2 different levels, pilot and full projects:

Pilot Projects
Pilot projects up to $25,000 can be applied for on a rolling basis but will be considered quarterly. Pilot projects will typically be for a six-month period with specific milestones defined with the intent of participation in the annual full Coulter award cycle. Apply using the same instructions with a focus on the necessary steps that will position PI for a successful full CCTRP application the following year. The individual component sections can be scaled back, but the PI is responsible for making his/her case. There are no CCTRP OC presentations for pilot projects.
 
Full Projects
Full projects will typically be for an initial one-year period with specific milestones defined on a quarterly basis; in special circumstances, proposals can span more than one year but must be approved prior to submission. Continuation and renewal applications will be evaluated on a competitive basis with new applications, and must have a comparison of milestones achieved vs. those planned in the original award. An important part of the proposal is the commercialization opportunity and the idea or vision for the end product. Examples of preferred future outcomes include inventions, patents, improved diagnosis and treatment of disease, commercial products, licenses, commercial partnerships and start-up companies.